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Structure of 363-51-9
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2-Chloro-6-fluoroaniline features a strategically positioned chlorine and fluorine substituent on the aromatic ring, delivering enhanced electronic modulation and metabolic stability. This electron-deficient aniline derivative integrates efficiently into pharmaceutical intermediates and agrochemical scaffolds, offering improved reactivity in coupling processes under standard conditions.
2-Chloro-6-fluoroaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering orthogonal reactivity for nucleophilic substitution and coupling reactions. Its halogenated aromatic scaffold enables efficient diversification via Pd-catalyzed cross-coupling, while the primary amine facilitates conjugation with electrophiles or incorporation into heterocyclic frameworks. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring selective functional group handling.
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GHS Pictogram :
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H319-H331-H373
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: