(1,2-Thiazol-5-yl)methanol

Name: (1,2-Thiazol-5-yl)methanol
Brand: ChemScene
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CAS No. 1710-66-3
Cat. No. CS-0215637
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 1710-66-3

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Description

(1,2-Thiazol-5-yl)methanol features a reactive thiazole ring fused to a primary alcohol group, enabling direct functionalization in heterocyclic synthesis. This bench-stable, moisture-tolerant scaffold integrates readily into pharmaceutical intermediates and ligand design, offering a versatile handle for C–H activation and cross-coupling transformations under mild conditions.

Application

(1,2-Thiazol-5-yl)methanol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to thiazole-containing scaffolds via standard functional group interconversions. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and coupling reactions with broad functional group tolerance. The compound exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.

General Information

CAS No. 1710-66-3
Cat. No. CS-0215637
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₅NOS
Molecular Weight 115.15
Synonym(s) 5-Isothiazolylmethanol
SMILES C1=C(CO)SN=C1

Computational Chemistry Data

TPSA 33.12
LogP 0.6354
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Isothiazole compounds

Key Words

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(1,2-Thiazol-5-yl)methanol

CAS No. 1710-66-3

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