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Structure of 928664-98-6
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4-Isoxazoleboronic acid pinacol ester features a stable boronate ester moiety integrated into an isoxazole scaffold, enabling reliable coupling in Suzuki-Miyaura reactions. The pinacol protection enhances moisture tolerance and shelf stability while maintaining high reactivity under standard conditions. This bench-stable reagent facilitates efficient access to functionalized heterocycles in synthetic and medicinal chemistry workflows.
4-Isoxazoleboronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura coupling reactions. Its isoaxazole moiety provides a bioisostere of carboxylic acids and enables incorporation into heterocyclic scaffolds common in medicinal chemistry. The pinacol ester enhances stability and simplifies purification, while maintaining reactivity under standard catalytic conditions. Functions reliably in cross-coupling workflows with aryl and vinyl halides, facilitating rapid access to functionalized isoxazole derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: