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Structure of 171178-43-1
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5-Amino-2-fluoroisonicotinic acid features a strategically positioned amino group and fluorine atom on the pyridine ring, enabling enhanced electronic modulation and metabolic stability. This ortho-substituted scaffold integrates readily into bioactive heterocycles, offering high solubility and bench-stable handling under standard conditions.
5-Amino-2-fluoroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive molecules. Its ortho-fluoro and amino groups offer complementary reactivity for palladium-catalyzed couplings, cyclizations, and derivatization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: