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Structure of 17129-06-5
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4-Ethoxy-1,1,1-trifluoro-3-buten-2-one reacts with phenylmagnesium bromide to afford ethoxy group substitution products, while it reacts with organozinc compounds to yield products arising from 1,2-addition to the carbonyl group. 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one on heating with triethyl phosphite affords [4+2] cycloaddition product, 2,2,2-triethoxy 2,3-dihydro-3-ethoxy-5-trifluoromethyl-1,25-oxaphospholene, which on hydrolysis affords a 2-oxo-2-hydroxy-2, 3-dihydro-3-hydroxy 5-trifluoromethyl-1,25-oxaphospholen. It reacts with amino to give the N-protected amino acids, which is useful for the peptide synthesis.4-Ethoxy-1,1,1-trifluoro-3-buten-2-one may be used in the synthesis of 4-dialkylamino-1,1,1-trifluorobut-3-ene-2-ones. It may be used for the synthesis of -alkyl- or dialkylamino substituted enones bearing a CF3 group.
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GHS Pictogram :
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GHS No : GHS02,GHS08
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Signal Word : Warning
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UN#: 1224
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H351-H412
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P273-P280-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: