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*For research and further manufacturing use only, not for direct human use.
Structure of 171723-95-8
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This trifluorinated amide integrates a hydroxymethyl-functionalized benzyl group, enabling direct conjugation or derivatization in synthetic workflows. The electron-withdrawing trifluoromethyl moiety enhances stability and modulates reactivity, while the pendant hydroxyl group offers a handle for further functionalization under standard conditions.
2,2,2-Trifluoro-N-(4-(hydroxymethyl)benzyl)acetamide serves as a versatile bifunctional building block in medicinal chemistry, combining a trifluoromethyl ketone precursor with a pendant benzyl alcohol. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the hydroxymethyl moiety enables facile derivatization via oxidation, etherification, or esterification. Its bench-stable nature and compatibility with standard protecting group strategies facilitate integration into multi-step syntheses of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: