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Structure of 123986-64-1
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tert-Butyl 4-(hydroxymethyl)benzylcarbamate features a benzylcarbamate scaffold with a pendant hydroxymethyl group, enabling selective derivatization at the alcohol site. The tert-butyl carbamate moiety provides stable protection for primary amines under standard conditions, while the benzylic hydroxyl offers compatibility with oxidation and coupling reactions. This bifunctional reagent streamlines synthesis of complex intermediates in medicinal chemistry and peptide modification workflows.
tert-Butyl 4-(hydroxymethyl)benzylcarbamate serves as a versatile building block in medicinal chemistry, enabling the synthesis of benzylated scaffolds through orthogonal deprotection strategies. The hydroxymethyl group facilitates downstream functionalization via oxidation or coupling reactions, while the carbamate moiety offers stable protection under standard conditions. Its bench stability and compatibility with diverse reaction environments make it well-suited for multi-step synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: