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CS-W001157 4
Total: USD 88.00

4-Methylbenzenesulfonic acid 2-methoxyethyl ester

  • CAS No. 17178-10-8

  • Cat. No. CS-W023070
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Methylbenzenesulfonic acid 2-methoxyethyl ester|CS-W023070

Structure of 17178-10-8

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Description

4-Methylbenzenesulfonic acid 2-methoxyethyl ester features a hydrolytically stable sulfonate ester linkage paired with a para-methyl aromatic group, enabling selective activation in synthetic sequences. The 2-methoxyethyl moiety enhances solubility in polar organic solvents while maintaining compatibility with bench-stable handling protocols. This compound serves as a tunable protecting group for alcohols in complex molecular architectures.

Application

4-Methylbenzenesulfonic acid 2-methoxyethyl ester serves as a robust, bench-stable protecting group for alcohols and amines, enabling selective deprotection under mild acidic conditions. Its orthogonal stability to many reaction types facilitates complex molecule synthesis. The ester functions effectively in coupling reactions and heterocycle formation, offering clean handling and straightforward purification—ideal for medicinal chemistry and process development workflows.

General Information

  • CAS No. 17178-10-8
  • Cat. No. CS-W023070
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄O₄S
  • Molecular Weight 230.28
  • Synonym(s) p-Toluenesulfonic Acid 2-Methoxyethyl Ester
  • SMILES O=S(C1=CC=C(C)C=C1)(OCCOC)=O

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.34672
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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