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Structure of 1722-10-7
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3-Chloro-6-methoxypyridazine is a heterocyclic building block featuring a chlorine atom at the 3-position and a methoxy group at the 6-position, enabling selective functionalization in synthetic routes. This electron-deficient pyridazine core facilitates cross-coupling reactions and integrates readily into bioactive scaffolds. The compound exhibits stability under standard bench conditions and offers enhanced solubility in common organic solvents, streamlining handling in process development workflows.
3-Chloro-6-methoxypyridazine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C3 position via palladium-catalyzed cross-coupling reactions. The chloro group exhibits high reactivity in Suzuki, Negishi, and Stille couplings, while the methoxy substituent provides moderate electron-donating character and enhances solubility. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: