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Structure of 172217-02-6
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7-(Trifluoromethyl)-1H-indole features a trifluoromethyl group at the 7-position of the indole core, conferring enhanced electron-withdrawing character and metabolic stability. This substitution pattern improves solubility in organic media while preserving the heterocycle’s reactivity for C–H functionalization and transition-metal-catalyzed coupling reactions. The molecule serves as a valuable scaffold in medicinal chemistry and materials science.
7-(Trifluoromethyl)-1H-indole serves as a valuable building block in medicinal chemistry, enabling direct incorporation of a strongly electron-withdrawing trifluoromethyl group at the C7 position of the indole core. Its bench-stable nature and compatibility with standard cross-coupling reactions facilitate efficient functionalization for drug discovery applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: