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CS-W001157 4
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Ethyl isoxazole-5-carboxylate

  • CAS No. 173850-41-4

  • Cat. No. CS-0044017
  • Purity≥97%
  • MDL No.MFCD18830699
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl isoxazole-5-carboxylate|CS-0044017

Structure of 173850-41-4

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Description

Ethyl isoxazole-5-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a reactive isoxazole ring. This compound integrates readily into synthetic sequences, serving as a key intermediate for bioactive molecule construction. Its electron-deficient core facilitates efficient coupling reactions and enables rapid diversification in medicinal chemistry applications.

Application

Ethyl isoxazole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted isoxazoles via standard coupling and functionalization protocols. Its ethyl ester group facilitates nucleophilic addition and metal-catalyzed transformations, while the isoxazole core provides inherent stability and compatibility with diverse reaction conditions. Widely used in medicinal chemistry and agrochemical research, it functions as a key scaffold for bioactive molecule construction due to its predictable reactivity and ease of purification.

General Information

  • CAS No. 173850-41-4
  • Cat. No. CS-0044017
  • Purity ≥97%
  • MDL No. MFCD18830699
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₃
  • Molecular Weight 141.12
  • Synonym(s) ethyl 1,2-oxazole-5-carboxylate
  • SMILES O=C(C1=CC=NO1)OCC

Computational Chemistry Data

  • TPSA   52.33
  • LogP   0.8513
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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