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2-Cyclopropylpropan-2-amine hydrochloride

  • CAS No. 17397-13-6

  • Cat. No. CS-0039123
  • Molecule weight135.64
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Cyclopropylpropan-2-amine hydrochloride|CS-0039123

Structure of 17397-13-6

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General Information

  • CAS No. 17397-13-6
  • Cat. No. CS-0039123
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClN
  • Molecular Weight 135.64
  • Synonym(s) 2-Cyclopropylpropan-2-Amine Hydrochloride(WX600264)
  • SMILES CC(C)(C1CC1)N.Cl

Description

2-Cyclopropylpropan-2-amine hydrochloride is a sterically hindered, bench-stable amine salt featuring a tertiary cyclopropyl-substituted carbon center. This configuration enhances stability and reduces nucleophilicity, making it ideal for use in asymmetric synthesis and as a chiral auxiliary in catalytic transformations.

Application

2-Cyclopropylpropan-2-amine hydrochloride serves as a stable, bench-ready amine building block for medicinal chemistry and catalytic synthesis. Its tertiary amine functionality enables efficient salt formation and enhances solubility in polar solvents, facilitating purification and handling. The cyclopropylpropan-2-amine core provides steric bulk and metabolic stability, commonly utilized in the construction of bioactive heterocycles and API scaffolds. Functions effectively in nucleophilic substitution and reductive amination protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.5555
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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