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CS-W001157 4
Total: USD 88.00

(3aS,3a'S,8aR,8a'R)-2,2'-(Propane-2,2-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)

  • CAS No. 175166-51-5

  • Cat. No. CS-0064059
  • Molecule weight358.43
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3aS,3a'S,8aR,8a'R)-2,2'-(Propane-2,2-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)|CS-0064059

Structure of 175166-51-5

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General Information

  • CAS No. 175166-51-5
  • Cat. No. CS-0064059
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₂N₂O₂
  • Molecular Weight 358.43
  • Synonym(s) (3aS,3'aS,8aR,8'aR)-2,2'-(1-Methylethylidene)bis[3a,8a-dihydro-8H-Indeno[1,2-d]oxazole
  • SMILES CC(C1=N[C@@H](C(C=CC=C2)=C2C3)[C@@H]3O1)(C)C4=N[C@@H]5[C@@H](CC6=C5C=CC=C6)O4

Description

This bicyclic oxazole scaffold features a rigid, electron-deficient core stabilized by steric shielding from the gem-dimethyl group. It integrates readily into chiral ligands and catalysts for asymmetric synthesis, offering high configurational integrity under standard bench conditions.

Application

(3aS,3a'S,8aR,8a'R)-2,2'-(Propane-2,2-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole) serves as a robust chiral scaffold for asymmetric synthesis, leveraging its rigid, polycyclic framework to enforce stereochemical control. The indeno[1,2-d]oxazole core exhibits excellent bench stability and functional group tolerance, enabling diverse transformations including metal-catalyzed cross-couplings and nucleophilic substitutions. Its orthogonal reactivity profile facilitates sequential derivatization in complex molecule assembly, making it a practical building block for advanced heterocyclic systems and target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   4.202
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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