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Structure of 175277-73-3
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Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)pyridine-5-carboxylate features a trifluoromethyl group that enhances electron deficiency and metabolic stability. The cyano and ester functionalities enable efficient coupling reactions, while the chloro substituent facilitates palladium-catalyzed cross-coupling. This compound serves as a key intermediate in synthesizing bioactive heterocycles for pharmaceutical development under standard conditions.
Ethyl 2-chloro-3-cyano-6-(trifluoromethyl)pyridine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to complex pyridine-based scaffolds. The molecule combines orthogonal functional groups—chloro, cyano, trifluoromethyl, and ester—that facilitate sequential transformations via cross-coupling, nucleophilic substitution, and cyclization reactions. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: