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CS-W001157 4
Total: USD 88.00

2,3,4,5-Tetrahydro-1H-benzo[c]azepine hydrochloride

  • CAS No. 17724-36-6

  • Cat. No. CS-W018800
  • Molecule weight183.68
  • Purity≥97%
  • MDL No.MFCD12198423

*For research and further manufacturing use only, not for direct human use.

2,3,4,5-Tetrahydro-1H-benzo[c]azepine hydrochloride|CS-W018800

Structure of 17724-36-6

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General Information

  • CAS No. 17724-36-6
  • Cat. No. CS-W018800
  • Purity ≥97%
  • MDL No. MFCD12198423
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄ClN
  • Molecular Weight 183.68
  • Synonym(s) 2,3,4,5-Tetrahydro-1H-benzo-[c]azepine hydrochloride
  • SMILES [H]Cl.C12=CC=CC=C1CNCCC2

Description

2,3,4,5-Tetrahydro-1H-benzo[c]azepine hydrochloride is a bench-stable, moisture-tolerant heterocyclic scaffold featuring a saturated seven-membered ring fused to benzene. This rigid, electron-rich core integrates readily into medicinal chemistry libraries, serving as a key structural motif for CNS-targeted compounds and bioactive molecules requiring enhanced metabolic stability and favorable pharmacokinetic profiles.

Application

2,3,4,5-Tetrahydro-1H-benzo[c]azepine hydrochloride serves as a stable, bench-ready heterocyclic building block for medicinal chemistry and process development. Its saturated azepine core exhibits favorable functional group tolerance and facilitates efficient derivatization via standard amine alkylation or electrophilic substitution. The hydrochloride salt enhances solubility and handling, enabling straightforward incorporation into multi-step syntheses of bioactive scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.1442
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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