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Structure of 1780710-91-9
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6-Bromo-3-methyl-1H-indole-2-carboxylic acid features a brominated indole core with a methyl group at the 3-position and a carboxylic acid at C2, enabling direct coupling in cross-coupling reactions. The electron-deficient aryl moiety enhances reactivity in Pd-catalyzed transformations. This bench-stable derivative serves as a key scaffold for bioactive molecule synthesis.
6-Bromo-3-methyl-1H-indole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid facilitates amide formation and derivatization. The methyl substituent enhances metabolic stability and modulates electronic properties. This compound exhibits good bench stability and is compatible with standard purification methods, making it ideal for constructing complex indole-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: