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Structure of 1783418-59-6
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This trifluoromethylcyclopropylmethanamine hydrochloride features a rigid cyclopropyl scaffold bearing a trifluoromethyl group and a primary amine, delivering enhanced metabolic stability and lipophilic character. The hydrochloride salt ensures excellent solubility and handling under standard conditions, enabling straightforward incorporation into medicinal chemistry campaigns targeting CNS-penetrant or kinase-inhibitory scaffolds.
(1-(Trifluoromethyl)cyclopropyl)methanamine hydrochloride serves as a stable, bench-ready building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its trifluoromethyl-cyclopropyl motif imparts enhanced metabolic stability and lipophilicity, while the amine functionality enables facile incorporation into diverse scaffolds via standard amidation, alkylation, or reductive amination protocols. The hydrochloride salt ensures improved crystallinity and handling, facilitating purification and scale-up in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: