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Structure of 1784428-43-8
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5-Bromopyridazin-4-ol features a bromine substituent at the 5-position and a hydroxyl group at the 4-position of the pyridazinone core, enabling direct functionalization in late-stage diversification. The electron-deficient heterocycle supports nucleophilic substitution reactions under mild conditions. This bench-stable scaffold integrates readily into bioactive molecule design.
5-Bromopyridazin-4-ol serves as a versatile building block in medicinal chemistry, enabling direct functionalization via palladium-catalyzed cross-coupling reactions. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the hydroxyl group offers site-specific derivatization potential. The compound exhibits good bench stability and facilitates efficient access to substituted pyridazinone scaffolds common in bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: