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Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride

  • CAS No. 179022-43-6

  • Cat. No. CS-0048910
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride|CS-0048910

Structure of 179022-43-6

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General Information

  • CAS No. 179022-43-6
  • Cat. No. CS-0048910
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆ClNO₂
  • Molecular Weight 205.68
  • Synonym(s) None
  • SMILES Cl.COC(=O)C1CC2CCC(C1)N2

Description

Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride features a rigid, nitrogen-containing bicyclic scaffold that imparts conformational stability and enhanced solubility. This bench-stable salt integrates readily into medicinal chemistry campaigns, serving as a key building block for targeted synthesis of bioactive alkaloids and CNS-directed pharmacophores.

Application

Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride serves as a versatile bicyclic scaffold for medicinal chemistry and synthetic organic applications. The protonated nitrogen enhances solubility and directs regioselective functionalization, while the ester group enables sequential transformations including reduction, amidation, and coupling reactions. Its bench-stable crystalline form facilitates handling and purification, making it ideal for building complex heterocyclic architectures in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.1118
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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