N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine

Name: N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 179552-75-1
Cat. No. CS-0160391
Purity≥97%
MDL No.MFCD30342451

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine|CS-0160391

Structure of 179552-75-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine features a quinazoline core bearing a methoxy group at C7 and diamino substituents at C4 and C6. The para-chloro-fluoro aryl moiety enhances target affinity, while the electron-rich diamine system facilitates conjugation in kinase inhibitor scaffolds. This compound integrates readily into medicinal chemistry campaigns targeting ATP-binding domains.

Application

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine serves as a key intermediate in the synthesis of kinase inhibitors and other bioactive heterocycles. Its dual amine functionality enables facile coupling reactions, while the 3-chloro-4-fluorophenyl and methoxy substituents provide enhanced solubility and metabolic stability. The compound exhibits bench-stable handling and is compatible with standard peptide and amide coupling protocols.

General Information

CAS No. 179552-75-1
Cat. No. CS-0160391
Purity ≥97%
MDL No. MFCD30342451
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₁₂ClFN₄O
Molecular Weight 318.73
Synonym(s) N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine
SMILES NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OC

Computational Chemistry Data

TPSA 73.06
LogP 3.7567
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

179552-75-1 sigma179552-75-1 manufacturer179552-75-1 price179552-75-1 structure179552-75-1 SDSbuy 179552-75-1179552-75-1 supplier179552-75-1 uses179552-75-1 molecular weightprice of 179552-75-1179552-75-1 chemical name formula of 179552-75-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine

CAS No. 179552-75-1

Recommended Products