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CS-W001157 4
Total: USD 88.00

2-Fluoro-3-nitrophenol

  • CAS No. 179816-26-3

  • Cat. No. CS-W006025
  • Purity≥98%
  • MDL No.MFCD11042443
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-3-nitrophenol|CS-W006025

Structure of 179816-26-3

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Description

2-Fluoro-3-nitrophenol features a fluorine atom at the ortho position and a nitro group at the meta position relative to the phenolic hydroxyl, creating a strongly electron-deficient aromatic system. This combination enhances reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The compound exhibits bench-stable handling characteristics and serves as a key intermediate in pharmaceutical synthesis and functional material design.

Application

2-Fluoro-3-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the phenolic oxygen and ortho-fluorine site. Its dual electrophilic handles facilitate nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions. The molecule exhibits bench stability and tolerates a range of reaction conditions, simplifying purification and integration into complex molecular architectures such as heterocyclic scaffolds and pharmaceutical intermediates.

General Information

  • CAS No. 179816-26-3
  • Cat. No. CS-W006025
  • Purity ≥98%
  • MDL No. MFCD11042443
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄FNO₃
  • Molecular Weight 157.10
  • Synonym(s) 2-fluoranyl-3-nitro-phenol
  • SMILES FC1=C([N+]([O-])=O)C=CC=C1O

Computational Chemistry Data

  • TPSA   63.37
  • LogP   1.4395
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H317-H318-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

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