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Structure of 179816-26-3
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2-Fluoro-3-nitrophenol features a fluorine atom at the ortho position and a nitro group at the meta position relative to the phenolic hydroxyl, creating a strongly electron-deficient aromatic system. This combination enhances reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The compound exhibits bench-stable handling characteristics and serves as a key intermediate in pharmaceutical synthesis and functional material design.
2-Fluoro-3-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the phenolic oxygen and ortho-fluorine site. Its dual electrophilic handles facilitate nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions. The molecule exhibits bench stability and tolerates a range of reaction conditions, simplifying purification and integration into complex molecular architectures such as heterocyclic scaffolds and pharmaceutical intermediates.
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: