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CS-W001157 4
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tert-Butyl 4-oxo-3,4-dihydroquinoline-1(2H)-carboxylate

  • CAS No. 179898-00-1

  • Cat. No. CS-0035613
  • Purity≥97%
  • MDL No.MFCD10697721
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-oxo-3,4-dihydroquinoline-1(2H)-carboxylate|CS-0035613

Structure of 179898-00-1

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Description

tert-Butyl 4-oxo-3,4-dihydroquinoline-1(2H)-carboxylate features a rigid, electron-deficient quinoline core with a masked carbonyl functionality, enabling direct incorporation into synthetic sequences without pre-activation. This bench-stable derivative facilitates efficient access to complex heterocycles through controlled cyclization or coupling reactions under standard conditions.

Application

tert-Butyl 4-oxo-3,4-dihydroquinoline-1(2H)-carboxylate serves as a versatile scaffold for the synthesis of quinoline-based heterocycles, enabling efficient access to medicinally relevant architectures. Its functionality supports diverse transformations including nucleophilic additions, reductive aminations, and transition-metal-catalyzed couplings. The tert-butyl ester group provides excellent bench stability and facilitates straightforward deprotection under mild acidic conditions, enhancing its utility in multi-step synthetic sequences.

General Information

  • CAS No. 179898-00-1
  • Cat. No. CS-0035613
  • Purity ≥97%
  • MDL No. MFCD10697721
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇NO₃
  • Molecular Weight 247.29
  • Synonym(s) N-Boc-3,4-dihydroquinoline-4(2H)-one
  • SMILES CC(C)(C)OC(=O)N1CCC(=O)C2=CC=CC=C21

Computational Chemistry Data

  • TPSA   46.61
  • LogP   3.0145
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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