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Structure of 402-12-0
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3-Fluoro-4-nitrobenzotrifluoride features a trifluoromethyl group flanked by strategically positioned fluorine and nitro substituents, delivering high electron deficiency for enhanced reactivity in cross-coupling processes. This bench-stable arylating agent integrates readily into complex molecular architectures under standard conditions.
3-Fluoro-4-nitrobenzotrifluoride serves as a versatile electrophilic building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its dual activating trifluoromethyl and nitro groups. The ortho-fluorine facilitates nucleophilic aromatic substitution, while the meta-nitro group enhances reactivity under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it valuable for constructing complex heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: