(R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol

Name: (R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1799412-23-9
Cat. No. CS-0095514
Purity≥97%
MDL No.MFCD25459280

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol|CS-0095514

Structure of 1799412-23-9

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Description

(R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol is a chiral building block featuring a pyridine core functionalized with chlorine and iodine at adjacent positions, enabling transition-metal-catalyzed coupling reactions. The (R)-configured amino alcohol moiety provides stereochemical control in the synthesis of bioactive molecules, particularly in kinase inhibitors and pharmaceutical intermediates. This compound exhibits stability under standard handling conditions and integrates readily into multi-step synthetic sequences.

Application

(R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol serves as a versatile building block in the synthesis of functionalized pyridine derivatives. Its iodine handle enables palladium-catalyzed cross-coupling reactions, while the chiral amino-alcohol functionality provides a site for further derivatization or incorporation into bioactive scaffolds. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative medicinal chemistry campaigns and API intermediate development.

General Information

CAS No. 1799412-23-9
Cat. No. CS-0095514
Purity ≥97%
MDL No. MFCD25459280
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀ClIN₂O
Molecular Weight 312.54
Synonym(s) None
SMILES C[C@@H](NC1=NC=C(Cl)C(I)=C1)CO

Computational Chemistry Data

TPSA 45.15
LogP 2.1323
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Iodide

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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(R)-2-((5-Chloro-4-iodopyridin-2-yl)amino)propan-1-ol

CAS No. 1799412-23-9

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