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CS-W001157 4
Total: USD 88.00

3-Aminoquinoline-8-carboxylic acid

  • CAS No. 1799412-39-7

  • Cat. No. CS-0460356
  • Molecule weight188.18
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Aminoquinoline-8-carboxylic acid|CS-0460356

Structure of 1799412-39-7

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General Information

  • CAS No. 1799412-39-7
  • Cat. No. CS-0460356
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈N₂O₂
  • Molecular Weight 188.18
  • Synonym(s) 3-Amino-8-quinolinecarboxylic acid
  • SMILES O=C(C1=CC=CC2=CC(N)=CN=C21)O

Description

3-Aminoquinoline-8-carboxylic acid features a fused quinoline core with strategically positioned amino and carboxylic acid groups, enabling versatile conjugation in medicinal chemistry. This scaffold integrates readily into bioactive molecules, offering enhanced solubility and hydrogen bonding capacity for target engagement.

Application

3-Aminoquinoline-8-carboxylic acid serves as a versatile building block for medicinal chemistry and materials science, enabling the construction of bioactive heterocycles through standard amide coupling, Suzuki-Miyaura, and Buchwald-Hartwig reactions. Its dual functional groups—amine and carboxylic acid—offer orthogonal reactivity for modular synthesis, while its inherent stability facilitates purification and handling on both laboratory and process scales.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   76.21
  • LogP   1.5152
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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