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Structure of 180340-70-9
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Methyl 6-amino-5-bromonicotinate features a brominated pyridine core with a strategically positioned amino group, enabling direct functionalization in late-stage synthesis. This bench-stable derivative integrates readily into heterocyclic scaffolds, offering enhanced reactivity for pharmaceutical intermediates and agrochemical development under standard conditions.
Methyl 6-amino-5-bromonicotinate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at both the amino and bromo sites. The ortho-halogenation facilitates palladium-catalyzed cross-coupling reactions, while the free amine allows for acylation, alkylation, or heterocycle formation. Its bench-stable nature and compatibility with standard protecting group strategies make it ideal for modular synthesis of complex scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: