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Structure of 1803416-30-9
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(S)-5-CF3-Pyox-iPr is a bench-stable, moisture-tolerant chiral pyridoxal derivative featuring a trifluoromethyl group at the 5-position and an isopropyl substituent. This configuration enhances electron-withdrawing character and steric control, enabling precise stereochemical delivery in asymmetric synthesis. The scaffold integrates readily into catalytic systems requiring robust, functionalized aldehyde equivalents.
(S)-5-CF₃-Pyox-iPr serves as a robust chiral auxiliary for asymmetric synthesis, enabling stereoselective transformations through its stable pyrrolidine scaffold. The trifluoromethyl group enhances electronic modulation and metabolic stability, while the isopropyl substituent improves solubility and facilitates purification. It functions effectively in enantioselective alkylations and conjugate additions, offering high diastereoselectivity and operational simplicity in standard bench-scale protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: