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Structure of 132187-16-7
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(R)-iPr-Pyox is a bench-stable, chiral pyridine-based ligand featuring a sterically hindered isopropyl group and a pyridoxal-derived core. This configuration enhances enantioselectivity in transition-metal catalysis, particularly in asymmetric allylic alkylation and conjugate addition reactions. The ligand integrates seamlessly into palladium- and nickel-catalyzed transformations under mild conditions.
(R)-iPr-Pyox serves as a highly effective chiral auxiliary in asymmetric synthesis, enabling stereoselective enolate formation and subsequent C–C bond construction. Its isopropyl-substituted pyrrolidine core provides excellent stereocontrol and bench stability, while facilitating straightforward purification and functional group tolerance. Widely employed in the synthesis of bioactive molecules, it functions reliably across standard organic transformations, including aldol reactions and alkylation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: