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Structure of 1806416-26-1
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4-Fluoro-3-hydroxypicolinic acid features a strategically positioned fluorine atom and hydroxyl group on the picolinic acid scaffold, enabling enhanced hydrogen bonding and polarity. This combination improves solubility and facilitates integration into bioactive scaffolds. The compound serves as a key building block for medicinal chemistry campaigns targeting kinase inhibitors and metal-chelating agents.
4-Fluoro-3-hydroxypicolinic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its ortho-hydroxyquinoline scaffold enables facile cyclization, metal coordination, and derivatization under standard conditions. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the hydroxyl group provides a handle for selective functionalization. Bench-stable and compatible with common coupling reactions, it facilitates efficient synthesis of complex scaffolds in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: