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Structure of 1808997-86-5
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This boronate moiety integrates a 2,4-difluoro-6-methoxyphenyl scaffold, offering enhanced stability and solubility in polar solvents. The electron-deficient aryl core enables efficient coupling under standard Suzuki-Miyaura conditions, while the methoxy group improves handling and reduces protodeboronation.
(2,4-Difluoro-6-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures under mild conditions. The ortho-difluoro substitution enhances electrophilic reactivity and facilitates downstream functionalization, while the methoxy group provides steric and electronic modulation. Bench-stable and readily purified by recrystallization, it exhibits excellent functional group tolerance, making it ideal for late-stage diversification in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: