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CS-W001157 4
Total: USD 88.00

AR antagonist 1 hydrochloride

  • CAS No. 1818885-55-0

  • Cat. No. CS-0137032
  • Purity≥98%
  • MDL No.MFCD30729667

*For research and further manufacturing use only, not for direct human use.

AR antagonist 1 hydrochloride|CS-0137032

Structure of 1818885-55-0

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General Information

  • CAS No. 1818885-55-0
  • Cat. No. CS-0137032
  • Purity ≥98%
  • MDL No. MFCD30729667
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₀Cl₂N₂O
  • Molecular Weight None
  • Synonym(s) None
  • SMILES [H]Cl.N#CC1=CC=C(O[C@H]2C(C)(C)[C@H](N)C2(C)C)C=C1Cl

Description

AR antagonist 1 (hydrochloride) delivers potent and selective inhibition of the androgen receptor, enabling precise modulation in hormone-sensitive biological systems. This bench-stable compound features enhanced solubility in aqueous media, facilitating consistent performance across cell-based assays and in vitro studies.

Application

AR antagonist 1 (hydrochloride) serves as a well-characterized tool compound for studying androgen receptor signaling pathways. It functions as a potent, selective ligand that binds competitively to the androgen receptor’s ligand-binding domain, inhibiting downstream transcriptional activity. Its hydrochloride salt form enhances solubility and stability in aqueous buffers, enabling consistent performance in cell-based assays and in vitro binding studies. This compound facilitates mechanistic investigations into hormone-dependent cancer biology and supports screening campaigns targeting androgen-responsive systems.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.04
  • LogP   3.77418
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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