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Structure of 1821378-64-6
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Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH features a conformationally constrained serine analog with a rigid psi(Me,Me)pro linkage, enhancing peptide backbone stability. The Trt-protected glutamine and Fmoc group enable efficient solid-phase synthesis, while the modified residue improves proteolytic resistance and structural fidelity in bioactive peptide sequences.
Fmoc-Gln(Trt)-Ser(ψ(Me,Me)Pro)-OH serves as a key building block for the synthesis of peptide scaffolds featuring constrained serine residues. The psi(Me,Me)Pro motif introduces a rigid, stable turn-inducing element that enhances conformational control in bioactive peptides. The Trt-protected glutamine and Fmoc-labeled amine enable orthogonal handling in solid-phase peptide synthesis, offering excellent stability and straightforward purification. This derivative facilitates efficient incorporation of structurally defined, protease-resistant motifs into complex peptide architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: