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Structure of 183736-74-5
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6-Chloro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid features a fused chromenone scaffold with orthogonal functional groups enabling diverse derivatization. The electron-deficient aromatic ring pairs with a phenolic hydroxyl and carboxylic acid for enhanced reactivity in coupling and cyclization processes. This bench-stable, moisture-tolerant compound serves as a key intermediate in the synthesis of bioactive heterocycles and natural product analogs.
6-Chloro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid serves as a versatile scaffold for the synthesis of bioactive chromenone derivatives. Its ortho-hydroxyketone motif enables facile cyclization and metal-catalyzed coupling reactions, while the carboxylic acid group supports derivatization via amide or ester formation. The molecule exhibits bench stability and tolerates common functional groups, facilitating efficient access to substituted coumarin-based building blocks used in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: