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Structure of 183741-86-8
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This protected pyridine carboxylic acid features a tert-butoxycarbonyl group that enables selective deprotection during peptide coupling, while the methoxy substituent enhances solubility and modulates electronic properties. The scaffold serves as a key intermediate in synthesizing bioactive heterocycles and pharmaceutical candidates requiring controlled functionalization.
5-((tert-Butoxycarbonyl)amino)-2-methoxyisonicotinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and medicinal chemistry intermediates. The tert-butoxycarbonyl (Boc) group provides stable protection of the primary amine, enabling orthogonal deprotection under mild acidic conditions. The methoxy and carboxylic acid functionalities offer complementary sites for derivatization, supporting diverse coupling reactions and cyclization strategies in peptide and small-molecule synthesis. Its bench-stable, crystalline form facilitates handling and purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: