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CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate

  • CAS No. 184042-58-8

  • Cat. No. CS-0109760
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate|CS-0109760

Structure of 184042-58-8

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General Information

  • CAS No. 184042-58-8
  • Cat. No. CS-0109760
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁FN₂O₂
  • Molecular Weight 232.30
  • Synonym(s) 1-Piperazinecarboxylic acid,4-(2-fluoroethyl)-,1,1-dimethylethyl ester
  • SMILES O=C(N1CCN(CCF)CC1)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      762-49-2
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~88%
    • tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate|CS-0109760
      184042-58-8

    References

    • BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; Härter, Michael; Beck, Hartmut; Ellinghaus, Peter; Berhörster, Kerstin; Greschat, Susanne; Thierauch, Karl-Heinz; Süssmeier, Frank Patent: US2013/196964 A1, 2013 ; Location in patent: Paragraph 1097; 1098; 1099; 1100 ;
  • Route2

    References

    • Breyholz, Hans-Joerg; Wagner, Stefan; Faust, Andreas; Riemann, Burkhard; Hoeltke, Carsten; Hermann, Sven; Schober, Otmar; Schaefers, Michael; Kopka, Klaus ChemMedChem, 2010 , vol. 5, # 5 p. 777 - 789
  • Route3
    • null|null
      762-51-6
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~%
    • tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate|CS-0109760
      184042-58-8

    References

    • Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh Patent: US2008/300242 A1, 2008 ; Location in patent: Page/Page column 74; 118 ; US 20080300242 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.78
  • LogP   1.5086
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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