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CS-W001157 4
Total: USD 88.00

Pyrazolo[1,5-a]pyridin-6-ol

  • CAS No. 184473-24-3

  • Cat. No. CS-0433356
  • Purity≥98%
  • MDL No.MFCD12026318

*For research and further manufacturing use only, not for direct human use.

Pyrazolo[1,5-a]pyridin-6-ol|CS-0433356

Structure of 184473-24-3

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General Information

  • CAS No. 184473-24-3
  • Cat. No. CS-0433356
  • Purity ≥98%
  • MDL No. MFCD12026318
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O
  • Molecular Weight 134.14
  • Synonym(s) 6-hydroxypyrazolo[1,5-a]pyridine
  • SMILES OC1=CN2C(C=C1)=CC=N2

Description

Pyrazolo[1,5-a]pyridin-6-ol delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry applications. This bench-stable core integrates readily into kinase inhibitors and other bioactive molecules, offering enhanced metabolic stability and favorable binding interactions through its polar hydroxyl group and planar structure.

Application

Pyrazolo[1,5-a]pyridin-6-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through established coupling and functionalization protocols. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient access to complex molecular architectures. The compound functions as a key intermediate in the development of kinase inhibitors and other targeted therapeutics, offering predictable reactivity in cross-coupling and electrophilic substitution reactions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   37.53
  • LogP   1.0399
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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