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Structure of 287953-54-2
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Benzyl 4-(chlorosulfonyl)piperidine-1-carboxylate features a reactive chlorosulfonyl group enabling direct sulfonation of nucleophiles. This bench-stable, moisture-tolerant reagent integrates seamlessly into synthetic sequences requiring sulfonyl transfer, offering high functional group compatibility and clean reaction profiles under standard conditions.
Benzyl 4-(chlorosulfonyl)piperidine-1-carboxylate serves as a versatile synthetic intermediate for constructing piperidine-based scaffolds. The chlorosulfonyl group enables efficient derivatization via nucleophilic substitution, facilitating the installation of diverse amine functionalities. Its benzyl ester moiety offers stability and ease of removal under standard hydrogenolysis conditions. This reagent demonstrates robust functional group tolerance and is well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: