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Structure of 18542-42-2
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SPDP-PEG4-acid is a PEG linker containing SPDP crosslinker and carboxylic acid moieties. SPDP is reactive toward thiol groups and contains a cleavable disulfide bond. Its membrane permeability allows for intracellular crosslinking reactions. The terminal caboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic properties of the PEG linkers increase compound solubility in aqueous media.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2734
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Class : 8 (3)
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Packing Group : Ⅱ
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Hazard Statements : H226-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: