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CS-W001157 4
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3-Amino-5-(4-chlorophenyl)thiophene-2-carboxylic acid

  • CAS No. 187949-86-6

  • Cat. No. CS-0188206
  • Molecule weight253.70
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Amino-5-(4-chlorophenyl)thiophene-2-carboxylic acid|CS-0188206

Structure of 187949-86-6

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General Information

  • CAS No. 187949-86-6
  • Cat. No. CS-0188206
  • Purity ≥96%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈ClNO₂S
  • Molecular Weight 253.70
  • Synonym(s) 3-amino-5-(4-chlorophenyl)-2-thiophenecarboxylic acid
  • SMILES C1=C(C=CC(=C1)Cl)C2=CC(=C(C(=O)O)S2)N

Synthesis

  • Route1

    References

    • WO2007/11284 A1, ; Page/Page column 22-23 ; WO 2007/011284 A1
  • Route2

    References

    • Synthesis, , # 15 art. no. Z07410SS, p. 2543 - 2546
  • Route3
    • 3-Chloro-3-(4-chlorophenyl)-2-propenenitrile|CS-0647594
      78583-86-5
    • ~%
    • 3-Amino-5-(4-chlorophenyl)thiophene-2-carboxylic acid|CS-0188206
      187949-86-6

    References

    • European Journal of Medicinal Chemistry, , vol. 65, p. 223 - 231

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   3.3489
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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