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Structure of 188577-68-6
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4,5-Dichloropyridin-2-amine features a pyridine core substituted with chlorine atoms at the 4 and 5 positions and an amino group at C2, delivering high reactivity in cross-coupling and nucleophilic substitution reactions. The electron-deficient aromatic ring enables efficient coupling with palladium catalysts, while the primary amine serves as a versatile handle for further functionalization. This bench-stable compound integrates readily into complex molecule synthesis.
4,5-Dichloropyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its dual chloro substituents offer orthogonal reactivity for sequential functionalization, while the pyridin-2-amine core provides a robust handle for further derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: