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Structure of 188781-10-4
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2-Chloro-4-methylpyrimidine-5-carboxylic acid features a pyrimidine core bearing a chloro group at C2, a methyl substituent at C4, and a carboxylic acid function at C5. This arrangement imparts enhanced reactivity in cross-coupling and cyclization processes, enabling efficient integration into bioactive heterocycles under standard conditions.
2-Chloro-4-methylpyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its electrophilic chlorine and carboxylic acid functionalities facilitate nucleophilic substitution and amidation reactions under mild conditions. The molecule exhibits good bench stability and facilitates purification via recrystallization, supporting scalable synthesis of bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: