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CS-W001157 4
Total: USD 88.00

N-Acetyl-L-proline

  • CAS No. 68-95-1

  • Cat. No. CS-W004114
  • Molecule weight157.17
  • Purity≥95%
  • MDL No.MFCD00020837

*For research and further manufacturing use only, not for direct human use.

N-Acetyl-L-proline|CS-W004114

Structure of 68-95-1

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General Information

  • CAS No. 68-95-1
  • Cat. No. CS-W004114
  • Purity ≥95%
  • MDL No. MFCD00020837
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁NO₃
  • Molecular Weight 157.17
  • Synonym(s) None
  • SMILES OC([C@H]1N(CCC1)C(C)=O)=O

Description

Acetylating L-proline’s pyrrolidine ring, N-Acetyl-L-proline (CAS 68-95-1) enhances peptide backbone rigidity to suppress enzymatic degradation and improves blood–brain barrier penetration in neuropharmacological assays.

Application

N-Acetyl-L-proline (CAS 68-95-1) drives pharmaceutical development by serving as a key building block in synthesizing neuroactive compounds targeting neurological disorders. It enhances peptide stability and bioactivity in therapeutic designs. Researchers leverage this compound to probe protein folding dynamics and enzyme mechanisms. Its moisturizing traits make it valuable in cosmetic formulations, while its role as a flavor stabilizer extends shelf life in food applications.

Synthesis

  • Route1
    • null|null
      75-36-5
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~82%
    • In-stock
      N-Acetyl-L-proline|CS-W004114
      68-95-1

    References

    • Thorat, Prashant B.; Goswami, Santosh V.; Khade, Bhimrao C.; Bhusare, Sudhakar R. Tetrahedron Asymmetry, 2012 , vol. 23, # 17 p. 1320 - 1325
  • Route2
    • null|null
      108-24-7
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~96%
    • In-stock
      N-Acetyl-L-proline|CS-W004114
      68-95-1

    References

    • Veera Reddy; Ravindranath Synthetic Communications, 1992 , vol. 22, # 2 p. 257 - 264
  • Route3
    • null|null
      2311-25-3
    • ~%
    • In-stock
      N-Acetyl-L-proline|CS-W004114
      68-95-1

    References

    • Tetrahedron Letters, , vol. 48, # 46 p. 8230 - 8233

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.61
  • LogP   0.0819
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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