N-Acetyl-L-proline

Name: N-Acetyl-L-proline
Brand: ChemScene
Availability: InStock
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CAS No. 68-95-1
Cat. No. CS-W004114
Purity≥95%
MDL No.MFCD00020837

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 68-95-1

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Description

N-Acetyl-L-proline features a stabilized proline scaffold with enhanced solubility and reduced racemization risk. This acetylated derivative integrates seamlessly into peptide synthesis workflows, offering reliable incorporation in diverse sequences. Its bench-stable nature supports consistent performance under standard conditions.

Application

N-Acetyl-L-proline serves as a stable, bench-ready proline derivative widely used in peptide synthesis and catalytic asymmetric reactions. Its acetylated nitrogen enhances solubility and reduces side reactions, while the cyclic pyrrolidine backbone provides defined stereochemistry and conformational rigidity. Functions effectively as a building block in peptidomimetics and supports efficient coupling protocols with minimal racemization.

General Information

CAS No. 68-95-1
Cat. No. CS-W004114
Purity ≥95%
MDL No. MFCD00020837
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₁NO₃
Molecular Weight 157.17
Synonym(s) None
SMILES OC([C@H]1N(CCC1)C(C)=O)=O

Computational Chemistry Data

TPSA 57.61
LogP 0.0819
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Natural Products

Bioactive Molecules Peptides

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids Biologically-modified Amino Acids

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N-Acetyl-L-proline

CAS No. 68-95-1

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