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Structure of 189278-27-1
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2-Bromo-6-(trifluoromethyl)pyridine features a trifluoromethyl group at the pyridine ring's para position, enhancing electron deficiency and enabling efficient cross-coupling. This bench-stable reagent integrates readily into Suzuki-Miyaura and Negishi reactions, delivering high yields in C–C bond formation under standard conditions.
2-Bromo-6-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity profile. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the bromine facilitates selective functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for constructing heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: