Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Isopropylpyrazole

  • CAS No. 18952-87-9

  • Cat. No. CS-W001098
  • Purity≥98%
  • MDL No.MFCD07468920

*For research and further manufacturing use only, not for direct human use.

1-Isopropylpyrazole|CS-W001098

Structure of 18952-87-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 18952-87-9
  • Cat. No. CS-W001098
  • Purity ≥98%
  • MDL No. MFCD07468920
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀N₂
  • Molecular Weight 110.16
  • Synonym(s) 2-isopropyl-1H-Pyrazole
  • SMILES CC(n1cccn1)C

Description

1-Isopropylpyrazole is a bench-stable, nitrogen-rich heterocycle featuring a pyrazole core substituted with an isopropyl group at the 1-position. This configuration imparts enhanced solubility in organic solvents and facilitates incorporation into pharmaceutical scaffolds. The molecule serves as a key building block for bioactive compounds, particularly in medicinal chemistry applications where modulating metabolic stability and lipophilicity is critical.

Application

1-Isopropylpyrazole serves as a versatile building block in medicinal chemistry, enabling the construction of pyrazole-based scaffolds prevalent in bioactive molecules. Its isopropyl group enhances lipophilicity and metabolic stability, while the pyrazole core offers hydrogen-bonding capacity and planar rigidity. The compound exhibits good bench stability and functional group tolerance, facilitating straightforward derivatization via electrophilic substitution or transition-metal-catalyzed coupling reactions. It functions effectively in the synthesis of heterocyclic APIs and agrochemical intermediates.

Synthesis

  • Route1
    • In-stock
      1H-pyrazole|CS-W008829
      288-13-1
    • null|null
      75-26-3
    • ~58%
    • In-stock
      1-Isopropylpyrazole|CS-W001098
      18952-87-9

    References

    • NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2006/108591 A1, 2006 ; Location in patent: Page/Page column 112 ; WO 2006/108591 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225-H315-H319
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P362-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.464
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Isopropylpyrazole sigma1-Isopropylpyrazole manufacturer1-Isopropylpyrazole price1-Isopropylpyrazole structure1-Isopropylpyrazole SDSbuy 1-Isopropylpyrazole1-Isopropylpyrazole supplier1-Isopropylpyrazole uses1-Isopropylpyrazole molecular weightprice of 1-Isopropylpyrazole1-Isopropylpyrazole chemical name formula of 1-Isopropylpyrazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label