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CS-W001157 4
Total: USD 88.00

3-(1H-imidazol-1-yl)propanoic acid

  • CAS No. 18999-45-6

  • Cat. No. CS-W002976
  • Purity≥95%
  • MDL No.MFCD02731119

*For research and further manufacturing use only, not for direct human use.

3-(1H-imidazol-1-yl)propanoic acid|CS-W002976

Structure of 18999-45-6

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General Information

  • CAS No. 18999-45-6
  • Cat. No. CS-W002976
  • Purity ≥95%
  • MDL No. MFCD02731119
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) TIMTEC-BB SBB007368
  • SMILES O=C(O)CCN1C=CN=C1

Description

3-(1H-imidazol-1-yl)propanoic acid features a polar imidazole ring linked via a three-carbon chain to a carboxylic acid group, enabling versatile conjugation in bioconjugation and medicinal chemistry. This scaffold integrates well into peptide architectures and offers enhanced solubility compared to aromatic analogs.

Application

3-(1H-Imidazol-1-yl)propanoic acid serves as a versatile building block for bioactive molecule synthesis, enabling the incorporation of imidazole functionality into pharmaceutical scaffolds. Its carboxylic acid group facilitates amide bond formation and conjugation reactions, while the imidazole ring provides hydrogen bonding capacity and metabolic stability. The compound exhibits good bench stability and is compatible with standard peptide coupling protocols, simplifying purification and integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.3578
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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