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Structure of 74784-70-6
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5-(Trifluoromethyl)pyridin-2-amine delivers a potent electron-deficient pyridine scaffold with enhanced solubility and stability. The trifluoromethyl group imparts strong lipophilicity and metabolic resistance, while the primary amine enables direct functionalization in late-stage diversification. This compound serves as a key building block for pharmaceutical intermediates and agrochemicals.
5-(Trifluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocycles via cross-coupling and electrophilic substitution. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridin-2-amine moiety provides a robust platform for further derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: