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Structure of 1904-24-1
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3-Ethyl-1H-pyrazol-5-amine features a pyrazole core with an ethyl substituent at the 3-position and a primary amine at the 5-position, enabling direct functionalization. This scaffold delivers enhanced solubility and stability compared to unsubstituted analogs, facilitating its use in medicinal chemistry and heterocyclic synthesis under standard conditions.
3-Ethyl-1H-pyrazol-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyrazole scaffolds via standard coupling and functionalization reactions. The molecule exhibits good bench stability and facilitates diverse transformations, including electrophilic substitution and metal-catalyzed cross-coupling, owing to its well-defined regiochemistry and moderate nucleophilicity at the C5 position. Its compatibility with common protecting group strategies and ease of purification make it a practical choice for lead optimization campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: