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Structure of 19056-40-7
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4-Bromo-3-methoxyaniline features a bromine substituent at the para position relative to the amino group and a methoxy group ortho to the amine, creating a uniquely functionalized aryl scaffold. This electron-rich aniline derivative enables direct coupling in palladium-catalyzed cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles and pharmaceuticals.
4-Bromo-3-methoxyaniline serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation into heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its bromo group facilitates Suzuki, Stille, and Buchwald–Hartwig couplings, while the methoxy and aniline functionalities offer orthogonal reactivity for downstream derivatization. The compound exhibits good bench stability and is readily purified by column chromatography, making it well-suited for scalable synthesis of functionalized arylamines.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: