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Structure of 19155-24-9
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This indolone scaffold features a sterically shielded, bench-stable core with enhanced solubility in polar organic solvents. The 3,3-dimethyl substitution prevents undesired side reactions at the C3 position, while the lactam functionality enables direct incorporation into bioactive molecule frameworks.
1,3-Dihydro-3,3-dimethyl-2H-indol-2-one serves as a stable, bench-ready building block for indole-based scaffolds. Its dimethyl-substituted C3 position enhances regiochemical control in electrophilic substitutions and facilitates functionalization at C2. The ketone moiety enables direct use in reductive amination, nucleophilic addition, and transition-metal-catalyzed coupling reactions. This compound functions effectively in the synthesis of heterocyclic intermediates and biologically relevant frameworks with predictable reactivity and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: