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CS-W001157 4
Total: USD 88.00

4-Chloro-3-methylaniline

  • CAS No. 7149-75-9

  • Cat. No. CS-W002307
  • Purity≥98%
  • MDL No.MFCD00066332
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-3-methylaniline|CS-W002307

Structure of 7149-75-9

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Description

4-Chloro-3-methylaniline is a chlorinated aniline derivative featuring a methyl group at the meta position relative to the amino function. This substitution pattern imparts enhanced electron density at the aromatic ring, facilitating electrophilic coupling reactions. The compound exhibits good bench stability and solubility in common organic solvents, enabling straightforward integration into synthetic sequences for pharmaceutical intermediates and agrochemical building blocks.

Application

4-Chloro-3-methylaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted anilines via standard coupling reactions. Its ortho-methyl group enhances metabolic stability and modulates electronic properties, while the chloro substituent provides a handle for palladium-catalyzed functionalization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable, multi-step synthetic sequences.

General Information

  • CAS No. 7149-75-9
  • Cat. No. CS-W002307
  • Purity ≥98%
  • MDL No. MFCD00066332
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClN
  • Molecular Weight 141.60
  • Synonym(s) 5-Amino-2-chlorotoluene~4-Chloro-m-toluidine; 4-Chloro-3-methylaniline
  • SMILES Nc1ccc(c(c1)C)Cl

Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.23062
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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